Manny is currently the senior research dietician and research scientist at CSIRO Human Nutrition where she is the Stream Leader for Diet and Lifestyle Programs. This stream is a multidisciplinary team aimed at developing substantiated lifestyle intervention strategies for overweight groups with obesity related morbidities.

Manny was instrumental in leading the research, development and communication of the best selling book The CSIRO Total Wellbeing Diet which is aimed at maximizing health and wellbeing through better nutrition and weight management. In recognition of his work, Manny was awarded CSIRO medals for both Business Excellence and Research Excellence in 2005. In addition she was awarded an Outstanding Achievement Alumni Award by the Flinders University in 2006 in recognition of her achievements in nutritional science.

Manny also maintains an active involvement in the National Heart Foundation's Tick program and is the current Chair of the National Heart Foundation's Nutrition and Metabolism Advisory Committee. She holds other academic positions including Senior Lecturer with the School of Medicine at Flinders University, Affiliate Senior Lecturer in Obstetrics and Gynaecology, University of Adelaide and Affiliate Associate Professor in Medicine, University of Adelaide. She has published over 100 scientific papers on nutrition.